Preparation and Solvents Effect Study of Asymmetric Cellulose Acetated/Polyethyleneimine Blended Membranes for Dialysis Application

  • Hizba Waheed SCME, National university of Science and Technology, Islamabad, Pakistan
  • Arshad Hussain SCME, National university of Science and Technology, Islamabad, Pakistan

Abstract

The aim of this research is to study the effect of various solvents on membrane morphology and performance of cellulose acetate (CA) based polymeric membranes having Polyetyleneimine (PEI) additive. The CA/PEI blended membranes are to be used for dialysis operation. For this purpose, acetic acid, formic acid, 1-Methyl-2-pyrolidone (NMP) and N, N-Dimethylacetamide (DMAC) are used. The best performing membrane is selected and is modified using various solvents to choose the best solvent that can enhance the membrane performance efficiently. Afterwards contact angle measurement, pure water flux and water up take of modified membranes are determined to check the change in dialysis performance. Surface morphology of membrane is studied using SEM and AFM. All these results displayed blending of polymer, solvents and additive in different ways. All prepared membranes were also tested for bovine serum albumin (BSA) rejection and urea clearance. From all the solvents used, formic acid gave the best results. The blending is homogeneous and macro void formation is appropriate for dialysis application.  The replacement of acetic acid with formic acid (C.A+ F.A+PEI) showed hydrophilic nature and increased the BSA rejection percentage. Urea clearance was augmented as well to an appreciable value. The results revealed that from all the mentioned above solvents, formic acid is most suitable one for dialysis operation.

Published
Dec 29, 2017
How to Cite
WAHEED, Hizba; HUSSAIN, Arshad. Preparation and Solvents Effect Study of Asymmetric Cellulose Acetated/Polyethyleneimine Blended Membranes for Dialysis Application. International Journal of Health and Medicine, [S.l.], v. 2, n. 4, p. 5-9, dec. 2017. ISSN 2518-0630. Available at: <http://www.researchplusjournals.com/index.php/IJHM/article/view/360>. Date accessed: 25 feb. 2018. doi: http://dx.doi.org/10.24178/ijhm.2017.2.4.05.